Welcome!
We are a neuroscience research team in The Wolfson Institute for Biomedical Research at University College London that investigates the neural basis of touch and pain. Our goal is to provide a mechanistic understanding of how the brain and behaviour shape the experience of touch and pain.
Pain alerts us to the threat of damage; it is protective and essential for survival. However, injury or pathology can affect this system leading to ongoing debilitating pain that is non-protective and without benefit. This represents a huge unmet clinical need. Chronic pain affects up to 20% of the population and treatments are often ineffective.
Our research team is investigating how the cortex and midbrain process sensory information and generate appropriate behaviours and pain. We apply advanced tools and technologies to investigate how the somatosensory system encodes and integrates information causing pain. This highly multidisciplinary approach is at the interface between neuroscience and engineering. We use two-photon calcium imaging, machine vision, optogenetics, electrophysiology, computational approaches, and viral and transgenic methods to address key questions using mice.
We are a neuroscience research team in The Wolfson Institute for Biomedical Research at University College London that investigates the neural basis of touch and pain. Our goal is to provide a mechanistic understanding of how the brain and behaviour shape the experience of touch and pain.
Pain alerts us to the threat of damage; it is protective and essential for survival. However, injury or pathology can affect this system leading to ongoing debilitating pain that is non-protective and without benefit. This represents a huge unmet clinical need. Chronic pain affects up to 20% of the population and treatments are often ineffective.
Our research team is investigating how the cortex and midbrain process sensory information and generate appropriate behaviours and pain. We apply advanced tools and technologies to investigate how the somatosensory system encodes and integrates information causing pain. This highly multidisciplinary approach is at the interface between neuroscience and engineering. We use two-photon calcium imaging, machine vision, optogenetics, electrophysiology, computational approaches, and viral and transgenic methods to address key questions using mice.
